By working with experts in the cosmetic and skin biology field, Nagase Personal Care designs and manages testing protocols to highlight the efficacy of its ingredients using innovative methods such as 3D skin equivalent models.   Reconstructed human skin or epidermis were developed at the end of the 1990s. Since the first basic in vitro models, which included only keratinocytes and fibroblasts, more complex models containing melanocytes, endothelial cells, immunocompetent cells or nerve cell...